Vitamin K

Disorders



Deficiency

The content of this vitamin, as same as vitamin E, in the diet usually significantly exceeds the minimum daily requirement and therefore the lack of this vitamin in the normal diet is extremely rare. In addition, vitamin K is synthesized by microorganisms in the colon.

In the absence of vitamin K in the body of animals are synthesized molecules of prothrombin, which are unable to properly bind calcium ions and thereby inhibit blood clot formation.

Common causes of vitamin K deficiency are low fat absorption syndromes associated with dysfunction of the pancreas, biliary tract, atrophy of the intestinal mucosa, or by any other cause of steatorrhea. In addition, sterilization of the colon, using orally taken antibiotics for a long period for elimination of bacterial flora, removes the most reliable source of vitamin K and can cause deficiency when the intake of vitamins from food is limited and when the diet is inadequate. Deficiency in this vitamin is caused by mineral oils, certain drugs (such as phenobarbital and some cephalosporin antibiotics).

Symptoms of vitamin K deficiency in the body are bruises on the body. There is celiac disease (stomach disease that is characterized by abdominal distension), tropical diseases, colitis (inflammation of the colon). It can occur diarrhea.

Overdose (hypervitaminosis, intoxication)

In exceded intake of vitamin K (over 500 micrograms per day) it may occur some allergic reactions such as skin rashes, itching and redness. Also occur liver problems, but they are not very common.

There is the potential toxicity of large doses of vitamin K, which can cause hemolysis in newborns and exacerbate hyperbilirubinemia.