Vitamin B1 plays a major role in the conversion of blood sugar (mainly glucose) into biological energy. It also participates in some key metabolic pathways in the nervous tissue, heart, red blood cells (erythrocytes). Plays an important role in the smooth and striated muscle.
In the tissues of humans and other animals, vitamin B1 is present in the form of thiamine pyrophosphate, which serves as a coenzyme in a series of enzymatic reactions where it process transferring of aldehyde group.
Vitamin B1 is absorbed in the intestine, and most of the exceeded products of its metabolism products are excreted in the urine and are not deposited. There is no evidence of the toxicity of this vitamin.