Physical and chemical properties
Vitamin B12 is very stable at high temperatures just if pH is ranged from 4.5 to 5.0 while the strong acidic and highly alkaline environment loses its vitamin activity.
This vitamin is rapidly degraded in the light, and therefore it is necessary to keep it in the dark. Vitamin B12 is negatively affected by alcohol, sleeping pills, estrogen, etc.
Vitamin B12 is well soluble in water, ethanol and methanol.
Under the term vitamin B12 several compounds that are similar in chemical structure are included. There are classified: cyanocobalamin, oxycobalamin, nitrocobalamin, aquacobalamin, etc.
In the structure of the vitamin B12 element cobalt is included. In the isolation of vitamin B12 we can get its cyanocobalamin derivative in which structure enters cyanide group, linked to an atom of cobalt.