Some of the bacteria can synthesise folic acid (vitamin B9) from p-amino benzoic acid. This discovery provided the ability to understand the mechanism of sulfanyl amides, which are used as medicines. Sulfanyl-amide inhibits the growth of pathogenic micro-organisms that have the need for p-aminobenzoic acid.
In patients with folic acid deficiency intaking of 300 to 500 micrograms of folate per day causes positive hematologic response.
Scientists from the U.S. National Cancer Institute in 1986. was found that the smokers with abnormal bronchial cells, the level of folic acid in the blood decreases, leading to an increased risk of cancer. Subsequent addition of folic acid and vitamin B12 may reduce the number of disordered bronchial cells and thus reduce the possibility of this disease. Although this study reduced the care for smokers, it should not be their excuse to continue smoking.
Folic acid (vitamin B9) plays an important role in the treatment of mental disorders. For children in prepuberty age adding this vitamin may increase the intelligence quotient. In older children, it is not observed.
Folic acid has a role in the treatment of atherosclerosis (narrowing of the arteries). Kurt Oster showed that giving patients up to 80 milligrams per day of folic acid may prevent heart attacks.